{"id":141,"date":"2024-12-14T20:57:02","date_gmt":"2024-12-14T20:57:02","guid":{"rendered":"https:\/\/thcparis.com\/?p=141"},"modified":"2024-12-14T20:57:02","modified_gmt":"2024-12-14T20:57:02","slug":"cannabis-et-cancer-utilite-therapeutique-en-oncologie-pour-calmer-les-douleurs","status":"publish","type":"post","link":"https:\/\/thcparis.com\/index.php\/2024\/12\/14\/cannabis-et-cancer-utilite-therapeutique-en-oncologie-pour-calmer-les-douleurs\/","title":{"rendered":"Cannabis et Cancer : Utilit\u00e9 th\u00e9rapeutique en oncologie pour calmer les douleurs"},"content":{"rendered":"

L\u2019utilit\u00e9 du cannabis th\u00e9rapeutique, notamment pour att\u00e9nuer les naus\u00e9es et les douleurs des patients trait\u00e9s pour un cancer, a fait l\u2019objet d\u2019une premi\u00e8re \u00e9tude exp\u00e9rimentale France en 2021.<\/p>\n

La France compte un certain retard \u00e0 cet \u00e9gard, de nombreux autres pays ayant d\u00e9j\u00e0 valid\u00e9 de longue date l\u2019usage du cannabis th\u00e9rapeutique dans le contr\u00f4le des naus\u00e9es et des douleurs en oncologie.<\/p>\n

Cette \u00e9tude, qui doit durer deux ans, porte davantage sur la faisabilit\u00e9 d\u2019une prise en charge des patients canc\u00e9reux \u00e0 l\u2019aide du cannabis th\u00e9rapeutique, que sur l\u2019efficacit\u00e9 de ce type de traitements.<\/p>\n

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Le cannabis m\u00e9dical en France<\/h2>\n

\"cannabis<\/p>\n

 <\/p>\n

Le\u00a0cannabis th\u00e9rapeutique<\/strong>, aujourd\u2019hui plus volontiers nomm\u00e9\u00a0cannabis m\u00e9dical en France<\/strong>, fait r\u00e9f\u00e9rence \u00e0 la plante\u00a0Cannabis Sativa<\/strong>\u00a0utilis\u00e9e sp\u00e9cifiquement dans un\u00a0contexte m\u00e9dical<\/strong>.<\/p>\n

Aussi, le\u00a0cannabis m\u00e9dical<\/strong>\u00a0n\u2019est pas vraiment\u00a0une vari\u00e9t\u00e9 particuli\u00e8re de Cannabis Sativa<\/strong>, mais un produit qui a\u00a0fait ses preuves<\/strong>\u00a0et\u00a0r\u00e9pond \u00e0 des standards pharmaceutiques<\/strong>.<\/p>\n

De fait, il existe de\u00a0nombreuses vari\u00e9t\u00e9s de Cannabis Sativa<\/strong>\u00a0qui pr\u00e9sentent des\u00a0taux de CBD et de THC \u2013<\/strong>\u00a0les substances actives principales du cannabis \u2013\u00a0diff\u00e9rents.<\/strong><\/p>\n

L\u2019usage de\u00a0cannabis th\u00e9rapeutique\u00a0<\/strong>implique un total contr\u00f4le de la\u00a0composition\u00a0<\/strong>des produits d\u00e9livr\u00e9s au patient, associ\u00e9es \u00e0 une\u00a0posologie pr\u00e9cise.<\/strong><\/p>\n

\u00a0<\/strong>En France, la consommation\u00a0tant r\u00e9cr\u00e9ative<\/strong>\u00a0que\u00a0th\u00e9rapeutique\u00a0<\/strong>de cannabis est\u00a0totalement ill\u00e9gale<\/strong>\u00a0\u2013 hors exp\u00e9rimentations cliniques en cours \u2013 tout comme sa vente et sa culture.<\/p>\n

L\u2019exp\u00e9rimentation en cours vise \u00e0 pr\u00e9parer une\u00a0potentielle l\u00e9galisation<\/strong>\u00a0de\u00a0cannabis m\u00e9dical<\/strong>, dont la\u00a0prescription\u00a0<\/strong>et\u00a0l\u2019administration<\/strong>\u00a0seront strictement encadr\u00e9es et r\u00e9serv\u00e9es \u00e0 un\u00a0contexte th\u00e9rapeutique.<\/strong><\/p>\n

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\u00a0<\/strong><\/p>\n

Dans quel cas le cannabis m\u00e9dical est-il indiqu\u00e9 ?<\/h2>\n

\"cannabis<\/p>\n

 <\/p>\n

Aujourd\u2019hui, le\u00a0cannabis th\u00e9rapeutique<\/strong>\u00a0est\u00a0en cours d\u2019exp\u00e9rimentation<\/strong>\u00a0et ne peut \u00eatre prescrit que par un\u00a0m\u00e9decin appartenant une structure de r\u00e9f\u00e9rence<\/strong>, associ\u00e9e \u00e0 l\u2019exp\u00e9rimentation.<\/p>\n

L\u2019exp\u00e9rience porte sur\u00a03 000 patients\u00a0<\/strong>souffrant de\u00a0maladies graves<\/strong>, dont l\u2019actuelle prise en charge est\u00a0inefficace ou insatisfaisante.<\/strong><\/p>\n

Chez ces patients, le\u00a0cannabis th\u00e9rapeutique\u00a0<\/strong>est indiqu\u00e9 pour tenter de\u00a0soulager des douleurs\u00a0<\/strong>auxquelles les\u00a0th\u00e9rapies traditionnelles\u00a0<\/strong>apportent une r\u00e9ponse insuffisante ou sont\u00a0mal tol\u00e9r\u00e9es<\/strong>.<\/p>\n

L\u2019exp\u00e9rimentation est centr\u00e9e sur\u00a05 indications th\u00e9rapeutiques<\/strong>\u00a0connues pour \u00eatre particuli\u00e8rement\u00a0r\u00e9fractaires aux th\u00e9rapies\u00a0<\/strong>aujourd\u2019hui disponibles pour\u00a0g\u00e9rer la douleur.<\/strong><\/p>\n

    \n
  1. La\u00a0premi\u00e8re indication<\/strong>\u00a0concerne les\u00a0douleurs neuropathiques<\/strong>, li\u00e9es aux\u00a0atteintes du syst\u00e8me nerveux<\/strong>.
    \nCes derni\u00e8res sont tr\u00e8s\u00a0d\u00e9licates \u00e0 traiter avec les th\u00e9rapies disponibles<\/strong>, et nombre de patients qui en souffrent se trouvent aujourd\u2019hui dans\u00a0une impasse th\u00e9rapeutique<\/strong>, sans solutions satisfaisantes, ce qui\u00a0alt\u00e8re profond\u00e9ment leur qualit\u00e9 de vie.<\/strong><\/li>\n
  2. Deuxi\u00e8me indication, les\u00a0raideurs douloureuses<\/strong>\u00a0(spasticit\u00e9s) de la\u00a0scl\u00e9rose en plaques\u00a0<\/strong>ou d\u2019autres\u00a0affections c\u00e9r\u00e9brales\u00a0<\/strong>(AVC, atteintes de la moelle \u00e9pini\u00e8re, etc.) , dont souffrent certains patients sans que les th\u00e9rapies actuelles ne permettent de les soulager efficacement.
    \nCe ph\u00e9nom\u00e8ne, encore\u00a0mal compris<\/strong>, a des\u00a0impacts n\u00e9fastes sur la sant\u00e9 des patients et leur qualit\u00e9 de vie<\/strong>, et reste aujourd\u2019hui souvent sans r\u00e9ponse th\u00e9rapeutique.<\/li>\n
  3. Une troisi\u00e8me indication est celle des\u00a0formes graves d\u2019\u00e9pilepsie<\/strong>\u00a0qui r\u00e9sistent aux traitements traditionnels.
    \nCertaines\u00a0\u00e9tudes internationales<\/strong>\u00a0sugg\u00e8rent d\u2019ores et d\u00e9j\u00e0 que le\u00a0cannabis th\u00e9rapeutique\u00a0<\/strong>pourrait avoir des b\u00e9n\u00e9fices significatifs pour les patients souffrants de ces pathologies.<\/li>\n
  4. La quatri\u00e8me indication cible les sympt\u00f4mes li\u00e9s\u00a0au cancer,\u00a0<\/strong>tel que\u00a0le cancer du sein<\/a>\u00a0et ses\u00a0traitements lourds<\/strong>\u00a0,\u00a0chimioth\u00e9rapie<\/a>, voir des affections \u00ab rebelles \u00bb, parfois impossibles \u00e0 contr\u00f4ler de mani\u00e8re satisfaisante.
    \nLes\u00a0douleurs\u00a0<\/strong>et les\u00a0naus\u00e9es\u00a0<\/strong>ressenties par le patient\u00a0    radioth\u00e9rapie<\/a>\u00a0canc\u00e9reux durant sa prise en charge sont, en effet, \u00e0 m\u00eame de\u00a0l\u2019affaiblir<\/strong>\u00a0et de\u00a0compromettre sa gu\u00e9rison sur le long terme.<\/strong><\/li>\n
  5. Enfin, cinqui\u00e8me et derni\u00e8re indication, l\u2019exp\u00e9rimentation se penche \u00e9galement sur les int\u00e9r\u00eats du\u00a0cannabis th\u00e9rapeutique\u00a0<\/strong>dans la prise en charge\u00a0palliative\u00a0<\/strong>de certains patients.
    \nUne prise en charge est dite\u00a0palliative\u00a0<\/strong>lorsqu\u2019une\u00a0gu\u00e9rison n\u2019est pas envisageable<\/strong>. Toutefois, une\u00a0situation palliative<\/strong>\u00a0n\u2019est pas synonyme de mort imminente\u00a0: il s\u2019agit parfois de\u00a0contr\u00f4ler durablement une maladie,<\/strong>\u00a0dans certains cas durant des ann\u00e9es, et il est donc essentiel de parvenir \u00e0 atteindre\u00a0une qualit\u00e9 de vie satisfaisante<\/strong>.<\/li>\n<\/ol>\n

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    \u00a0Cannabis et cancers gyn\u00e9cologiques : les effets th\u00e9rapeutiques<\/h2>\n

    \"cannabisL\u2019int\u00e9r\u00eat du\u00a0domaine oncologique<\/strong>\u00a0pour le\u00a0cannabis m\u00e9dical<\/strong>\u00a0ne fait que grandir ces derni\u00e8res ann\u00e9es, car de nombreuses \u00e9tudes internationales semblent d\u00e9montrer ses b\u00e9n\u00e9fices r\u00e9els.<\/p>\n

    Le\u00a0cannabis m\u00e9dical<\/strong>\u00a0pourrait permettre de contr\u00f4ler les\u00a0douleurs l\u00e9g\u00e8res et mod\u00e9r\u00e9es<\/strong>, mais aussi les\u00a0naus\u00e9es<\/strong>, les\u00a0vomissements<\/strong>, les\u00a0spasmes<\/strong>, les\u00a0insomnies<\/strong>\u2026 Soit une\u00a0panoplie d\u2019effets secondaires<\/strong>\u00a0qui accompagnent couramment\u00a0le cancer du sein\u00a0<\/strong>et les\u00a0traitements lourds<\/strong>\u00a0utilis\u00e9s pour le soigner.<\/p>\n

    Bien qu\u2019il ne soit\u00a0en aucun cas<\/strong>\u00a0envisag\u00e9 pour\u00a0remplacer les\u00a0traitements contre le cancer<\/a>\u00a0existants<\/strong>, le cannabis th\u00e9rapeutique pourrait apporter une\u00a0aide compl\u00e9mentaire<\/strong>\u00a0pour\u00a0soulager les patients canc\u00e9reux\u00a0<\/strong>en \u00e9vitant d\u2019ajouter une m\u00e9dication traditionnelle suppl\u00e9mentaire.<\/p>\n

    Le combat contre le cancer est une \u00e9preuve longue et \u00e9prouvante, qui peut mettre la sant\u00e9 de l\u2019organisme \u00e0 rude \u00e9preuve.<\/p>\n

    La douleur, les naus\u00e9es et les vomissements qui accompagnent fr\u00e9quemment la maladie et ses traitements sont susceptibles d\u2019affaiblir davantage le patient, notamment en engendrant d\u00e9nutrition et insomnie.<\/p>\n

    Or, la forme physique du patient durant son traitement et sa convalescence est un facteur cl\u00e9 d\u2019une bonne cicatrisation, qui favorise une gu\u00e9rison plus rapide et r\u00e9duit certains risques de s\u00e9quelles durables.<\/p>\n

    L\u2019usage du cannabis th\u00e9rapeutique en oncologie pour att\u00e9nuer les douleurs et les naus\u00e9es trouve donc toute son utilit\u00e9.<\/p>\n

     <\/p>\n

     <\/p>\n

     <\/p>\n

    \n

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    L\u2019utilit\u00e9 du cannabis th\u00e9rapeutique, notamment pour att\u00e9nuer les naus\u00e9es et les douleurs des patients trait\u00e9s pour un cancer, a fait l\u2019objet d\u2019une premi\u00e8re \u00e9tude exp\u00e9rimentale France en 2021. La France compte un certain retard \u00e0 cet \u00e9gard, de nombreux autres pays ayant d\u00e9j\u00e0 valid\u00e9 de longue date l\u2019usage du cannabis th\u00e9rapeutique dans le contr\u00f4le des 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